QbD Assisted Systematic Review for Optimizing the Selection of PVP as a Ternary Substance in Enhancing the Complexation Efficiency of Cyclodextrins: a Pilot Study

Inclusion complexes require higher concentration of Beta cyclodextrins (βCD) resulting in increased formulation bulk, toxicity, and production costs. This systematic review offers a comprehensive analysis using Quality by design (QbD) as a tool to predict potential applications of Polyvinylpyrrolidone ...

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Impacts of designed vanillic acid-polymer-magnetic iron oxide nanocomposite on breast cancer cells

The engineered nano-vehicle was constructed using magnetic iron oxide nanoparticles (MIONs) and chitosan (CTS) to stabilize anticancer agent vanillic acid (VNA) which was loaded on CTS-coated MIONs nanocarrier, and more importantly, to achieve sustained VNA release and subsequent proper anticancer...

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Home or abroad? Exploring medical students’ attitudes towards studying and working overseas

Background & Objective: Cross-border medical student mobility and doctor migration have become global trends. The aim of this study was to explore Malaysian medical students’ attitudes towards studying and working overseas. Materials & Methods: A cross-sectional study was conducted among ...

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Effect of coenzyme Q10 supplementation on post-vitrification mouse embryo development

Objective: To investigate the effects of coenzyme Q10 (CoQ10) supplementation on post-vitrification embryo development and gross morphology. Methods: Balb/c mouse embryos were cultured in potassium simplex optimised medium (KSOM) wit...

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Developing Muslim-friendly hospital practices: understanding the key drivers

Purpose The purpose of this study is to examine the appropriate components and sub-components of Muslim-friendly hospital practices that comply with Islamic medical ethics and Sharia requirements. Design/methodology/approach A systematic&#x...

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Reliability and Validation of MSCEIT to Evaluate Emotional Intelligence for Chronic Kidney Disease Patients

To evaluate the reliability and validate the method used to test for emotional intelligence(EI) among CKD patients. METHODOLOGY: This study was conducted in a public hospital for patients with kidney disease. A total of 30 CKD patients were included in this study using the fla...

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Molecular Docking Analysis of Christanoate and Christene from Christia vespertilionis Plants as Potential Inhibitors of Covid-19

Covid-19 is a global pandemic caused by SARS-CoV-2 virus that caused mortality and world economic collapse. It is almost impossi ble to break the chain of infection with no inter vention except vaccines to prevent worsening symptoms and to build herd immunity in people. Effort...

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Facile engineering of aptamer-coupled silk fibroin encapsulated myogenic gold nanocomposites: investigation of antiproliferative activity and apoptosis induction

Nanocomposites selectively induce cancer cell death, holding potential for precise liver cancer treatment breakthroughs. This study assessed the cytotoxicity of gold nanocomposites (Au NCs) enclosed within silk fibroin (SF), aptamer (Ap), and the myogenic Talaromyces purpureogenus (TP) against a human...

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Estimation of Heritability and Genetic Correlation of Quantitative Traits as a Basis for Selection Program of Indonesian Native Chickens

Native chicken is a potential genetic source to produce new superior and productive strains. The genetic parameter information is needed as basis data for the selection program to improve the genetic quality of native chickens. This study aimed to estimate the heritability and gene...

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Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells

Aspartame, a widely used artificial sweetener, is present in many food products and beverages worldwide. It has been linked to potential neurotoxicity and developmental defects. However, its teratogenic effect on embryonic development and the underlying potential mechanisms need to be elucidated....

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