Modulation of Sirtuin-1 by Resveratrol as A Potential Therapy in Alleviating Metabolic Syndrome

Objective: This review aims to investigate the therapeutic potential of resveratrol in managing metabolic syndrome, with particular emphasis on its molecular interaction with sirtuin-1 (SIRT1) and its downstream effects on cellular metabolism and signaling pathways. Methods: A comprehens...

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Development of Pressure Sensor Using Plastic Optical Fiber

This research presents the development of a high-sensitivity pressure sensor using plastic optical fibers (POFs), offering a safe, reliable, and cost-effective alternative to conventional sensors. A POF is modified into a U-shaped sensor by bending method and connected to a white light ...

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Development Of Water PH Sensor Using Plastic Optical Fiber

This project investigates the development and performance of a U-shaped Plastic Optical Fiber (POF) sensor designed for real-time water pH monitoring. The proposed sensor offers a low-cost, durable, and robust solution to overcome the limitations of traditional glass electrode-based pH sensors,&#...

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Anthropometric measurements of the external nose among Malay and Chinese: A Cross-sectional study from Sarawak, Malaysia

Nasal anthropometry is among the best clues to racial origin and sexual determination. The nose's shape and structure differ between genders, races, and ethnicities. The understanding of nasal anthropometry is applied in forensic medicine, nasal reconstruction surgery, and naso-facial dysmorpholog...

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An Integrated Metabolomics Study on Antidiabetic Activity of Christia vespertilionis Leaves Extract Using Chemometric and Molecular Docking Analysis

In disease treatment, the utilisation of medicinal plants has witnessed a discernible rise, driven by concerns over the adverse effects associated with synthetic drugs available in the market. Analyses of the plant Christia vespertilionis (L.f.) Bakh. F., indigenous to Malaysia, has suggeste...

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QbD Assisted Systematic Review for Optimizing the Selection of PVP as a Ternary Substance in Enhancing the Complexation Efficiency of Cyclodextrins: a Pilot Study

Inclusion complexes require higher concentration of Beta cyclodextrins (βCD) resulting in increased formulation bulk, toxicity, and production costs. This systematic review offers a comprehensive analysis using Quality by design (QbD) as a tool to predict potential applications of Polyvinylpyrrolidone ...

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Impacts of designed vanillic acid-polymer-magnetic iron oxide nanocomposite on breast cancer cells

The engineered nano-vehicle was constructed using magnetic iron oxide nanoparticles (MIONs) and chitosan (CTS) to stabilize anticancer agent vanillic acid (VNA) which was loaded on CTS-coated MIONs nanocarrier, and more importantly, to achieve sustained VNA release and subsequent proper anticancer...

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Effect of coenzyme Q10 supplementation on post-vitrification mouse embryo development

Objective: To investigate the effects of coenzyme Q10 (CoQ10) supplementation on post-vitrification embryo development and gross morphology. Methods: Balb/c mouse embryos were cultured in potassium simplex optimised medium (KSOM) wit...

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Developing Muslim-friendly hospital practices: understanding the key drivers

Purpose The purpose of this study is to examine the appropriate components and sub-components of Muslim-friendly hospital practices that comply with Islamic medical ethics and Sharia requirements. Design/methodology/approach A systematic&#x...

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Reliability and Validation of MSCEIT to Evaluate Emotional Intelligence for Chronic Kidney Disease Patients

To evaluate the reliability and validate the method used to test for emotional intelligence(EI) among CKD patients. METHODOLOGY: This study was conducted in a public hospital for patients with kidney disease. A total of 30 CKD patients were included in this study using the fla...

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