Cytotoxicity of Physalis minima Linn (Solanaceae) fruit against HCT116 and HT29 colorectal cancer cell lines

The pantropical Physalis minima are traditionally used for the prevention and treatment of various illnesses, diseases, and cancers. While most earlier studies on the species have focused on the phytochemistry of the leaf and stem extracts, recent studies have indicated that its fruit&#...

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Anthropometric measurements of the external nose among Malay and Chinese: A Cross-sectional study from Sarawak, Malaysia

Nasal anthropometry is among the best clues to racial origin and sexual determination. The nose's shape and structure differ between genders, races, and ethnicities. The understanding of nasal anthropometry is applied in forensic medicine, nasal reconstruction surgery, and naso-facial dysmorpholog...

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An Integrated Metabolomics Study on Antidiabetic Activity of Christia vespertilionis Leaves Extract Using Chemometric and Molecular Docking Analysis

In disease treatment, the utilisation of medicinal plants has witnessed a discernible rise, driven by concerns over the adverse effects associated with synthetic drugs available in the market. Analyses of the plant Christia vespertilionis (L.f.) Bakh. F., indigenous to Malaysia, has suggeste...

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QbD Assisted Systematic Review for Optimizing the Selection of PVP as a Ternary Substance in Enhancing the Complexation Efficiency of Cyclodextrins: a Pilot Study

Inclusion complexes require higher concentration of Beta cyclodextrins (βCD) resulting in increased formulation bulk, toxicity, and production costs. This systematic review offers a comprehensive analysis using Quality by design (QbD) as a tool to predict potential applications of Polyvinylpyrrolidone ...

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Impacts of designed vanillic acid-polymer-magnetic iron oxide nanocomposite on breast cancer cells

The engineered nano-vehicle was constructed using magnetic iron oxide nanoparticles (MIONs) and chitosan (CTS) to stabilize anticancer agent vanillic acid (VNA) which was loaded on CTS-coated MIONs nanocarrier, and more importantly, to achieve sustained VNA release and subsequent proper anticancer...

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Home or abroad? Exploring medical students’ attitudes towards studying and working overseas

Background & Objective: Cross-border medical student mobility and doctor migration have become global trends. The aim of this study was to explore Malaysian medical students’ attitudes towards studying and working overseas. Materials & Methods: A cross-sectional study was conducted among ...

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Effect of coenzyme Q10 supplementation on post-vitrification mouse embryo development

Objective: To investigate the effects of coenzyme Q10 (CoQ10) supplementation on post-vitrification embryo development and gross morphology. Methods: Balb/c mouse embryos were cultured in potassium simplex optimised medium (KSOM) wit...

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Developing Muslim-friendly hospital practices: understanding the key drivers

Purpose The purpose of this study is to examine the appropriate components and sub-components of Muslim-friendly hospital practices that comply with Islamic medical ethics and Sharia requirements. Design/methodology/approach A systematic&#x...

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Reliability and Validation of MSCEIT to Evaluate Emotional Intelligence for Chronic Kidney Disease Patients

To evaluate the reliability and validate the method used to test for emotional intelligence(EI) among CKD patients. METHODOLOGY: This study was conducted in a public hospital for patients with kidney disease. A total of 30 CKD patients were included in this study using the fla...

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Molecular Docking Analysis of Christanoate and Christene from Christia vespertilionis Plants as Potential Inhibitors of Covid-19

Covid-19 is a global pandemic caused by SARS-CoV-2 virus that caused mortality and world economic collapse. It is almost impossi ble to break the chain of infection with no inter vention except vaccines to prevent worsening symptoms and to build herd immunity in people. Effort...

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