1. Research Paper: Recent submissions

Now showing items 41-60 of 2255

Evaluation of curcumin nanoparticles of various sizes for targeting multidrug-resistant lung cancer cells via inhalation

Loo, Ching Yee ; Traini, Daniela; Young, Paul M.; Yeung, Stewart; Leong, Chean Ring; Lee, Wing Hin; (UniKL RCMP) (Taylor & Francis, 2024-12)

Introduction: Inhalation drug delivery can deliver high doses of chemotherapeutic drugs to the lung tumor. This study evaluates the efficacy and the mechanistic pathways of nebulized Cur NPs at various sizes to treat ...
Cultivating clean sport environment with athlete support personnel (ASP): A study on anti-doping knowledge, attitudes, and practices of ASP

Lim, Ming Chiang; Nair, Gobinathan; Chua, Eng Wee; Tuan Mazlelaa Tuan Mahmood; Farrah Hani Imran; Ahmad Fuad Shamsuddin; Adliah Mhd Ali; (UniKL RCMP) (Public Library of Science, 2024-12)

Athlete support personnel (ASP) work closely with, treat, or assist an athlete participating in or preparing for sports competition. Their involvement in preventing and eliminating doping is crucial. This study investigated ...
Combined and isolated effects of workstation ergonomics and physiotherapy in improving cervicogenic headache and work ability in office workers: a single-blinded, randomized controlled stud

Nambi, Gopal; Alghadier, Mshari; Mohamed, Shahul Hameed Pakkir; Vellaiya, Arul; Ebrahim, Elturabi Elsayed; Sobeh, Dena Eltabey; Kashoo, Faizan Z.; Albarakati, Alaa Jameel A.; Alshahrani, Naif A.; Eswaramoorthi, Vijayamurugan; (UniKL RCMP) (Frontiers, 2024-11)

Objective: The objective of the study is to compare and investigate the combined and individual effects of workstation ergonomics, physiotherapy and patient education in improving CgH headaches and work ability in office ...
Characterization of physicochemical, tribological, and sensory properties of dark chocolate incorporated with Nypa fruticans as a sugar alternative

Amirul Rasyid Ramli; So’bah Ahmad; Seow, Lay Jing; Addion Nizori; Law, Lin Hee; Seow, Eng Keng; (UniKL RCMP) (Springer Nature, 2024-12)

Dark chocolate is a popular snack, but its high sugar content raises health concerns. This study explores the potential of Nypa fruticans sugar (Gula Apong) as a natural sugar alternative to enhance the nutritional profile ...
Black Seed Oil-Alginate Nanoemulsion Characteristics Utilising an Ultrasonicator at Pilot Plant Scale

Shaiqah Mohd Rus; Anika Zafiah Mohd Rus; Awis Sukarni Mohmad Sabere; Mohd. Rushdi Abu Bakar; Farahidah Mohamed; Doolaanea, Abd Almonem; (UniKL RCMP) (Researchers Links Ltd, 2024-10)

Black seed oil (BSO) contains thymoquinone, an active ingredient that is well-known for its antioxidant property and used in food and traditional medicine. BSO is encapsulated in micrometre-sized alginate beads (AB), to ...
Role of Antimicrobial Peptides as Potential Arsenal Against SARS-CoV-2 and Other Pathogens

Fatin Fathia Mohd Ali; Anand, Daniel Alex; Blackard, Jason T.; Balakrishnan, Pachamuthu; Shanmugam, Saravanan; Pradeep, Palanisamy; Rehanna Mansor; Muhammad Imran Ahmad; Vignesh, Ramachandran; (UniKL RCMP) (Universiti Putra Malaysia Press, 2024-09)

Antimicrobial peptides (AMPs) represent a diverse group of short peptides that are widely distributed across various organisms and serve as essential defense agents. Their crucial role in combating the escalating threat ...
Formulation and in-vitro evaluation of electrospun microfibers for enhanced solubility of Olmesartan medoxomil

Sisinthy, Sreenivas Patro; Chai, Siew En; Majeed, Shahnaz; Nur Najihah ‘Izzati Mat Rani; (UniKL RCMP) (Open Science Publishers LLP Inc., 2024-04)

Olmesartan medoxomil (OLM), which is a biopharmaceutical classification system class II drug has low aqueous solubility, resulting in its poor bioavailability and therapeutic efficacy. In this present study, OLM was ...
Facile construction of gefitinib-loaded zeolitic imidazolate framework nanocomposites for the treatment of different lung cancer cells

Aiyasamy, Kalaivani; Ramasamy, Malathi; Hirad, Abdurahman Hajinur; Arulselvan, Palanisamy; Jaganathan, Ravindran; Suriyaprakash, Jagadeesh; Thangavelu, Indumathi; Alarfaj, Abdullah A.; (UniKL RCMP) (John Wiley and Sons Inc, 2024-08)

Gefitinib (GET) is a revolutionary targeted treatment inhibiting the epidermal growth factor receptor's tyrosine kinase action by competitively inhibiting the ATP binding site. In preclinical trials, several lung cancer ...
EXPERIMENTAL DEPRESSION-MODULATED ACTIVATION PATTERN OF THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS

Nur Amirah Diyana Razlan; Kapitonova, Marina; Alyautdin, Renad Nikolaevich; Saiful Bahri Talip; Norhida Ramli; Nwe, Tin Mo; (UniKL RCMP) (Avicenna Tajik State Medical University, 2024)

Objective: To study the effect of modelled depression not associated with stress on the hypothalamic-pituitary-adrenal system (HPAS) in mice. Methods: The experiment was conducted on the twenty-four C57BL/6 mice weighing ...
Comparative Analysis of In Vitro Photo-Protective Effects on Clitoria ternatea Ethanolic Extract

Aida Ayuni Mohd Noor Azwan Shah; Ain Qistina Allyssa Fadrullah; Amal Batrisyia Mohamed Afrizol; Khor, Poh Yen; (UniKL RCMP) (Malaysian Institute of Chemistry, 2024)

In this study, Clitoria ternatea flowers (CT) underwent four distinct ethanolic extraction procedures: maceration, soxhlet, ultrasonication-assisted extraction (UAE), and enzyme-assisted extraction (EAE). Analysis of the ...
Pemetrexed loaded gold nanoparticles as cytotoxic and apoptosis inducers in lung cancer cells through ROS generation and mitochondrial dysfunction pathway

P., Baby Shakila; Periasamy, Tamilmani; Alarfaj, Abdullah A.; Arulselvan, Palanisamy; Ravindran, Rajeswari; Suriyaprakash, Jagadeesh; Thangavelu, Indumathi; (UniKL RCMP) (John Wiley and Sons Inc, 2024-08)

Supramolecular nanoparticles containing peptides and drugs have recently gained recognition as an effective tumor treatment drug delivery system. A multitarget drug termed pemetrexed is effective against various cancers, ...
Knowledge, attitude and prevalence of ivermectin use as coronavirus disease treatment: A cross-sectional study among a Malaysian population

Filza Nur Athirah Tar’Ali; Aina Amanina Abdul Jalil; Nor Safwan Hadi Nor Afendi; (UniKL RCMP) (Academy of Family Physicians of Malaysia, 2024)

Introduction: During the coronavirus disease (COVID-19) pandemic, there was a widespread public misconception regarding ivermectin use in managing the disease. There is no approval of ivermectin as COVID-19 treatment by ...
The Toxicity of Mercury and Its Chemical Compounds: Molecular Mechanisms and Environmental and Human Health Implications: A Comprehensive Review

Wu, Yuan-Seng; Osman, Ahmed I; Hosny, Mohamed; Elgarahy, Ahmed M.; Eltaweil, Abdelazeem S.; Rooney, David W.; Chen, Zhonghao; Nur Syafiqah Rahim; Sekar, Mahendran; Gopinath, Subash C. B.; Nur Najihah ‘Izzati Mat Rani; Batumalaie, Kalaivani; Yap, Pow-Seng; (UniKL RCMP) (American Chemical Society, 2024-02)

Mercury is a type of hazardous and toxic pollutant that can result in detrimental effects on the environment and human health. This review is aimed at discussing the state-of-the-art progress on the recent developments on ...
Factors Affecting the Synthesis of Bovine Serum Albumin Nanoparticles Using the Desolvation Method

Tanjung, Yenni Puspita; Dewi, Mayang Kusuma; Gatera, Vesara Ardhe; Barliana, Melisa Intan; Joni, I. Made; Chaerunisaa, Anis Yohana; (UniKL RCMP) (Dove Medical Press Ltd, 2024)

Currently, protein-based nanoparticles are in high demand as drug delivery systems due to their exceptional qualities, including nontoxicity, nonantigenicity, and biodegradability. Other qualities include high nutritional ...
The effect of microwave and muffle furnace-assisted heating on the surface characteristics of teff husk activated carbons: Thermodynamic, isotherm, and kinetics study of Pb removal

Siraj, Khalida; Aballa, James Simon; Danish, Mohammed; Ahmad, Tanweer; Khan, Mohammad Mansoob; Majeed, Shahnaz; Adane, Birtukan; (UniKL RCMP) (Elsevier Ltd, 2024-03)

This study explored the fabrication of activated carbon from teff husk biomass using microwave and muffle-furnace-assisted heating and observed its effect on surface characteristics and the thermodynamics, isotherm, and ...
Tannic acid chitosan iron oxide nanocomposite for cervical cancer treatment

Barahuie, Farahnaz; Dorniani, Dena; Saifullah, Bullo; Arulselvan, Palanisamy; Hussein, Mohd Zobir; Jaganathan, Ravindran; Pratiwi, Ariyati Retno; (UniKL RCMP) (Elsevier B.V., 2024-04)

An innocuous and stimuli-responsive nano-vehicle was constructed from chitosan (CTS) and synthesized iron oxide (Fe3O4) nanoparticles. Tannic acid (TNA) was selected as a drug model to attest to the function of CTS-Fe3O4 ...
Corrigendum: Stylopine: a potential natural metabolite to block vascular endothelial growth factor receptor 2 (VEGFR2) in osteosarcoma therapy

Velayutham, Naveen Kumar; Thamaraikani, Tamilanban; Wahab, Shadma; Khalid, Mohammad; Ramachawolran, Gobinath; Abullais, Shahabe Saquib; Wong, Ling Shing; Sekar, Mahendran; Gan, Siew Hua; Ebenezer, Angel Jemima; Ravikumar, Mrinalini; Subramaniyan, Vetriselvan; Nur Najihah Izzati Mat Rani; Wu, Yuan Seng; Srikanth, Jeyabalan; (UniKL RCMP) (Frontiers Media SA, 2024-01)

In the published article, there was an error in the Article Title. Instead of “Stylopine: A potential natural metabolite to activate vascular endothelial growth factor receptor 2 (VEGFR2) in osteosarcoma therapy,” it should ...
Caralluma pauciflora based Ag-NPs activate ROS - induced apoptosis through down-regulation of AKT, mTOR and pI3K signaling in human gastric cancer (AGS) cells

Navaneethan, Renuga Devi; Packia, Lekshmi N.C.J.; Ramaiah, Mariselvam; Ravindran, Rajeswari; Tamilarasan, Ananth Kumar; Chinnathambi, Arunachalam; Ali Alharbi, Sulaiman; Sivagnanam, Ananthi; Mohemedibrahim, Ponnani Kaja Mideeni; (UniKL RCMP) (Institute of Physics, 2024-05)

The phytochemicals found in Caralluma pauciflora were studied for their ability to reduce silver nitrate in order to synthesise silver nanoparticles (AgNPs) and characterise their size and crystal structure. Thunbergol, ...
Wound healing and antidiabetic properties of green synthesized silver nanoparticles in 3T3-L1 mouse embryo fibroblast cells through 2-NBDG expression

Majeed, Shahnaz; Nursyafiqah Zainal Abidin; Muthukumarasamy, Ravindran; Danish, Mohammed; Afzan Mahmad; Mohamad Nasir Mohamad Ibrahim; Alanazi, Abdulaziz M.; Ansari, Mohammed Tahir; Sisinthy, Sreenivas Patro; (UniKL RCMP) (Elsevier B.V., 2024-01)

The antibacterial and antifungal properties of silver and silver-based compounds have been recognized for quite some time. This study employed an extracellular method to produce silver nanoparticles (AgNPs) using the leaves ...
A review of pre- and post-surface-modified neem (Azadirachta indica) biomass adsorbent: Surface functionalization mechanism and application

Karim, Abdul Rasheed; Danish, Mohammed; Alam, Mohd Gulfam; Majeed, Shahnaz; Alanazi, Abdulaziz M.; (UniKL RCMP) (Elsevier Ltd, 2024-03)

In contemporary wastewater treatment industry, advanced oxidation techniques, membrane filtration, ion exchange, and reverse osmosis are used to treat chemically loaded wastewater. All these methods required highly toxic ...

Now showing items 41-60 of 2255

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