1. Research Paper: Recent submissions

  • Surface-engineered liposomes for dual-drug delivery targeting strategy against methicillin-resistant Staphylococcus aureus (MRSA) 
    Nur Najihah Izzati Mat Rani ; Chen, Xiang Yi; Al-Zubaidi, Zahraa M; Hanisah Azhari; Tzar Mohd Nizam Khaithir; Ng, Pei Yuen; Fhataheya Buang; Tan, Geok Chin; Wong, Yin Ping; Mazlina Mohd Said; Butt, Adeel Masood; Azmy A Hamid; Mohd Cairul Iqbal Mohd Amin; (UniKL RCMP) (Shenyang Pharmaceutical University, 2022-01)
    This study focused on the encapsulation of vancomycin (VAN) into liposomes coated with a red blood cell membrane with a targeting ligand, daptomycin–polyethylene glycol–1,2-distearoyl-sn-glycero-3-phosphoethanolamine, ...
  • Outer membrane vesicles as biomimetic vaccine carriers against infections and cancers 
    Nur Najihah Izzati Mat Rani; Alzubaidi, Zahraa M; Butt, Adeel Masood; Nur Dini Fatini Mohammad Faizal; Sekar, Mahendran; Hanisah Azhari; Mohd Cairul Iqbal Mohd Amin; (UniKL RCMP) (John Wiley and Sons Inc, 2022-07)
    In the last decade, nanoparticle-based therapeutic modalities have emerged as promising treatment options for cancer and infectious diseases. To improve prognosis, chemotherapeutic and antimicrobial drugs must be delivered ...
  • Exploring the focal role of LRRK2 kinase in Parkinson’s disease 
    Kumar, Sachin; Behl, Tapan; Sehgal, Aayush; Chigurupati, Sridevi; Singh, Sukhbir; Mani, Vasudevan; Aldubayan, Maha; Alhowail, Ahmed; Kaur, Satvinder; Bhatia, Saurabh; Al-Harrasi, Ahmed; Subramaniyan, Vetriselvan; Fuloria, Shivkanya; Fuloria, Neeraj Kumar; Sekar, Mahendran; Abdel Daim, Mohamed M.; (UniKL RCMP) (Springer Science and Business Media Deutschland GmbH, 2022-05)
    The major breakthroughs in our knowledge of how biology plays a role in Parkinson's disease (PD) have opened up fresh avenues designed to know the pathogenesis of disease and identify possible therapeutic targets. Mitochondrial ...
  • Correlation of the GC-MS-based metabolite profile of Momordica charantia fruit and its antioxidant activity 
    Perumal, Vikneswari; Alfi Khatib; Ahmed, Qamar Uddin; Uzir, Bisha Fathamah; Faridah Abas; Murugesu, Suganya; Mohd Zuwairi Saiman; Primaharinastiti, Riesta; El-seedi, Hesham R.; (UniKL RCMP) (Universiti Putra Malaysia, 2022)
    Momordica charantia or bitter melon (Cucurbitaceae) is a widely consumed edible fruit with strong antioxidant properties. Due to these properties, it has been commercialised by the natural product industries as a coadjutant ...
  • Comparative Adsorption of Methylene Blue Dye on Hexane-Washed and Xanthated Spent Grated Coconut (Cocos nucifera L.): Isotherms, Thermodynamics, and Mechanisms 
    Khadijah Khalid; Megat Ahmad Kamal Megat Hanafiah; Al-Amrani, Waheeba A.; Nik Ahmad Nizam Nik Malek; Fatinathan, Sharon; (UniKL RCMP) (Polskie Towarzystwo Inzynierii Ekologicznej (PTIE), 2022)
    A batch system investigated the application of two types of chemically modified biosorbents derived from spent grated coconut (Cocos nucifera) powder to adsorb methylene blue (MB) from aqueous solutions. The biosorbents ...
  • Advanced drug delivery systems containing herbal components for wound healing 
    Gorain, Bapi; Pandey, Manisha; Leng, Ng Hui; Yan, Cho Wei; Nie, Kuek Wee; Kaur, Simran Jeet; Marshall, Vincent; Sisinthy, Sreenivas Patro; Panneerselvam, Jithendra; Molugulu, Nagashekhara; Kesharwani, Prashant; Choudhury, Hira; (UniKL RCMP) (Elsevier B.V., 2022-04)
    Management of chronic wound has an immense impact on social and economic conditions in the world. Healthcare costs, aging population, physical trauma, and comorbidities of diabetes and obesity seem to be the major factors ...
  • Systemic lupus erythematosus and antineutrophil cytoplasmic antibodies-associated vasculitis overlap in an elderly woman: A case-based literature review 
    Wahinuddin Sulaiman; Foong, Henry Boon Bee; Tan, Kah Wee; Yeap, Yean Lian; Lee, Bang Rom; (UniKL RCMP) (Egyptian Society for Joint Diseases and Arthritis, 2022-01)
    Background: The overlap of systemic lupus erythematosus (SLE) and anti-neutrophil cytoplasmic antibody (ANCA) associated-vasculitis (AAV) is a rare entity. Aim of the work: To report a rare case of overlap SLE and AAV ...
  • Genistein: A Potential Natural Lead Molecule for New Drug Design and Development for Treating Memory Impairment 
    Fuloria, Shivkanya; Muhamad Azrul Amir Yusri; Sekar, Mahendran; Gan, Siew Hua; Nur Najihah Izzati Mat Rani; Pei Teng, Lum; Ravi, Subban; Subramaniyan, Vetriselvan; Azad, Abul Kalam; Jeyabalan, Srikanth; Wu, Yuan Seng; Meenakshi, Dhanalekshmi Unnikrishnan; Sathasivam, Kathiresan V.; Fuloria, Neeraj Kumar; (UniKL RCMP) (MDPI, 2022-01)
    Genistein is a naturally occurring polyphenolic molecule in the isoflavones group which is well known for its neuroprotection. In this review, we summarize the efficacy of genistein in attenuating the effects of memory ...
  • Benefits and Challenges of Urban Air Mobility as Future Public Transportation in Malaysia: 
    Nor Hisham Ghafar, Ahmad Fikri Idham Mohd Jusoh, Nor Aida Abdul Rahman, Mohamed Idrus Abd Moin (UniKL MIAT) (2023-11-23)
    Urban air mobility (UAM), an emerging advanced aerial transportation within the urban and sub-urban areas, attracts the interest of numerous countries including Malaysia. Since developing this new transportation ecosystem ...
  • Advances in Polyhydroxyalkanoate Nanocarriers for Effective Drug Delivery: An Overview and Challenges 
    Prakash, Priyanka; Lee, Wing-Hin; Loo, Ching-Yee; Wong, Hau Seung Jeremy; Parumasivam, Thaigarajan; (UniKL RCMP) (MDPI, 2022-01)
    Polyhydroxyalkanoates (PHAs) are natural polymers produced under specific conditions by certain organisms, primarily bacteria, as a source of energy. These up-and-coming bioplastics are an undeniable asset in enhancing the ...
  • DENV-Mimetic Polymersome Nanoparticles Bearing Multi-Epitope Lipopeptides Antigen as the Next-Generation Dengue Vaccine 
    Nur Adilah Abdul Rahman; Abdin Shakirin Mohamad Norpi; Muhammad Luqman Nordin; Mohd Cairul Iqbal Mohd Amin; Abdullah Al-Hadi Ahmad Fuaad; Nor Azila Muhammad Azami; Marasini, Nirmal; Fazren Azmi; (UniKL RCMP) (MDPI, 2022-01)
    Dengue remains a severe threat to public health. The safety and efficacy of the licensed dengue vaccine is not clinically satisfactory, which necessitate the need of new approach in designing an effective dengue vaccine ...
  • Promising Natural Products in New Drug Design, Development, and Therapy for Skin Disorders: An Overview of Scientific Evidence and Understanding Their Mechanism of Action 
    Nurul Amirah Mohd Zaid; Sekar, Mahendran; Bonam, Srinivasa Reddy; Gan, Siew Hua; Lum, Pei Teng; Begum, Yasmin; Nur Najihah Izzati Mat Rani; Vaijanathappa, Jaishree; Wu, Yuan Seng; Subramaniyan, Vetriselvan; Fuloria, Neeraj Kumar; Fuloria, Shivkanya; (UniKL RCMP) (Dove Medical Press Ltd, 2022)
    The skin is the largest organ in the human body, composed of the epidermis and the dermis. It provides protection and acts as a barrier against external menaces like allergens, chemicals, systemic toxicity, and infectious ...
  • A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer 
    Subramaniyan, Vetriselvan; Fuloria, Shivkanya; Gupta, Gaurav; Darnal, Hari Kumar; Sekar, Mahendran; V. Sathasivam, Kathiresan; Sudhakar, Kalvatala; Alharbi, Khalid Saad; Al-Malki, Waleed Hassan; Afzal, Obaid; Kazmi, Imran; Al-Abbasi, Fahad A.; Altamimi, Abdulmalik Saleh Alfawaz; Fuloria, Neeraj Kumar; (UniKL RCMP) (Elsevier Ireland Ltd, 2022-01)
    Epithelial growth factor receptor (EGFR) is a cell surface transmembrane receptor that mediates the tyrosine signaling pathway to carry the extracellular messages inside the cell and thereby alter the function of nucleus. ...
  • Tilianin: A Potential Natural Lead Molecule for New Drug Design and Development for the Treatment of Cardiovascular Disorders 
    Farrah Syazana Khattulanuar; Sekar, Mahendran; Fuloria, Shivkanya; Gan, Siew Hua; Nur Najihah Izzati Mat Rani; Ravi, Subban; Chidambaram, Kumarappan; Begum, Yasmin; Azad, Abul Kalam; Jeyabalan, Srikanth; Dhiravidamani, Arulmozhi; Thangavelu, Lakshmi; Lum, Pei Teng; Subramaniyan, Vetriselvan; Wu, Yuan Seng; V. Sathasivam, Kathiresan; Fuloria, Neeraj Kumar; (UniKL RCMP) (MDPI, 2022-02)
    Cardiovascular disorders (CVDs) are the leading risk factor for death worldwide, and research into the processes and treatment regimens has received a lot of attention. Tilianin is a flavonoid glycoside that can be found ...
  • Kirenol: A Potential Natural Lead Molecule for a New Drug Design, Development, and Therapy for Inflammation 
    Naurah Nabihah Nasir; Sekar, Mahendran; Fuloria, Shivkanya; Gan, Siew Hua; Nur Najihah Izzati Mat Rani; Ravi, Subban; Begum, Yasmin; Chidambaram, Kumarappan; V. Sathasivam, Kathiresan; Jeyabalan, Srikanth; Dhiravidamani, Arulmozhi; Thangavelu, Lakshmi; Lum, Pei Teng; Subramaniyan, Vetriselvan; Wu, Yuan Seng; Azad, Abul Kalam; Fuloria, Neeraj Kumar; (UniKL RCMP) (MDPI, 2022-02)
    Kirenol, a potential natural diterpenoid molecule, is mainly found in Sigesbeckia species. Kirenol has received a lot of interest in recent years due to its wide range of pharmacological ac-tions. In particular, it has a ...
  • Government, Universities, and Private Companies Influences on Smart Cities Performance: Malaysia Perspectives 
    Khairul Azizan Suda; (UniKL MIDI) (2023-12-06)
    In empowering the performance and growth of smart cities in Malaysia, it is crucial to have a good grasp of the dynamic between different departments and teams within the government’s institutions. This dynamic is ...
  • Molecular and Epigenetic Basis of Extracellular Vesicles Cell Repair Phenotypes in Targeted Organ-specific Regeneration 
    Muhamad Fareez Ismail; Wu, Yuan Seng; Muhammad Zaki Ramli; Shafiq Aazmi; Mohamad Izwan Ismail; (UniKL RCMP) (Current Molecular Medicine, 2022-02)
    Extracellular vesicles (EVs), which are released by most of the cells, constitute a new system of cell-cell communication by transporting DNA, RNA, and proteins in various vesicles namely exosomes, apoptotic bodies, protein ...
  • Therapeutic Potential and Nutraceutical Profiling of North Bornean Seaweeds: A Review 
    Shah, Muhammad Dawood; Venmathi Maran, Balu Alagar; Sitti Raehanah Muhamad Shaleh; Wahidatul Husna Zuldin; Gnanaraj, Charles; Yong, Yoong Soon; (UniKL RCMP) (MDPI, 2022-02)
    Malaysia has a long coastline surrounded by various islands, including North Borneo, that provide a suitable environment for the growth of diverse species of seaweeds. Some of the important North Bornean seaweed species ...
  • High-fat Diet Increases Sprague-Dawley Corticosterone Blood Levels with Nominal Change in Adrenocorticotrophic hormone (ACTH) Level with Signs of Increased Mesenteric Adiposity 
    Khairil Azwan Malim Jaafar; Resni Mona; Firdous, Jannathul; Dina Keumala Sari; David, Pamela Rosie; Noorzaid Muhamad; (UniKL RCMP) (Prodia Education and Research Institute, 2022-03)
    BACKGROUND: Corticosterone is a common hormone in research involving rodents as it is used to indicate and measure stress levels. It was widely reported that certain dietary habits and components induce Hypothalamic ...
  • Eight weeks consumption of high-fat diet promotes Mesenteric fat deposition when compared to other rat diets 
    Khairil Azwan Malim Jaafar; Resni Mona; Firdous, Jannathul; Dina Keumala Sari; David, Pamela Rosie; Noorzaid Muhamad; (UniKL RCMP) (Research Journal of Pharmacy and Technology, 2022-02)
    Metabolic syndrome is a grouping of several medical conditions plaguing the modern world today. Excessive visceral fat is strongly associated with abdominal obesity which is one of the characteristics of metabolic syndrome. ...

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